Episode #1031

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        Why can we see Venus from Earth

        Questions and Emails

        I love the show, thanks for putting the effort to make such a great listening experience. I feel that when I found the podcast I finally found my clique! Just a correction to Caras segment on 23andme. 23andme does not sequence your DNA, they use microarrays that detect specific single nucleotide polymorphisms (SNP) in the sample. This is very different to actually sequencing your DNA. Im not familiar which array 23andme is using but typically they detect hundreds to thousands of SNPs. The validity of the SNPs genotyped, again not sequenced, can be dupious. A single SNP or even thousands of SNPs cannot be scientificly used to infer characteristics of a single person. They can only be used as aggregate data to determine risks or potential correlations to traits (phenotypes). Some SNPs are more common in certain populations which can be used to roughly estimate your ancestry. SNPs are not equal, some have been validated through rigorous research and can be said to be risk factors, such as some SNPs in the BRCA-gene. However, many SNPs used in arrays have no data to back them up, there is no validated correlation to any risk or phenotype. So, a good collection of alot of SNPs can tell something about a population where those SNPs are, but not really anything relevant about an individual. Actual sequencing a persons DNA is a complete different beast, but I wont go to that here. Please feel free to ask clarification or references on the subject. Best regards, Markus, a geneticist from the other side of the puddle, from a country that some deranged questionare has deemed the happiest in the world.

        Science or Fiction

        Skeptical Quote of the Week.

        ‘Science is not just a collection of techniques or strategies for producing knowledge, it is an ethical stance of commitment to the truth. The good scientist knows that honestly following the evidence is a form of respect for nature, and honestly communicating one’s findings is a form of respect for others.’ - Michael Anderson